ISARIC provides a collaborative platform through which global, patient‐oriented clinical studies can be developed, executed and shared.

Protocols addressing the most important questions between and during epidemics of severe acute respiratory infections and other rapidly emerging public health threats are undertaken in order to generate new knowledge, maximise the availability of clinical information, and thereby save lives.

Read more about our protocols by clicking this link.

ISARIC Stakeholders' Meeting Report

by Sarah Moore

One of the key lessons learnt from the 2014-15 Ebola outbreak research response effort in West Africa is that it is critical to establish excellent working relations and collaborations in ...

Outbreak Updates

You can sign up to the News Round-up to receive regular updates from ISARIC, including Outbreak Updates, Funding Opportunities, and Upcoming Events.


Zika Virus

Updates and guidelines

WHO and PAHO Initiative to Support 17 New Research Proposals on Zika in Seven Countries in Latin America and the Caribbean
23 Feb 2017 | WHO/PAHO
Zika Virus (ZIKV) Vaccine Target Product Profile (TPP): Vaccine to protect against congenital Zika syndrome for use during an emergency
23 Feb 2017 | WHO/UNICEF 


News and Media

How to use mosquitoes to combat disease
23 Feb 2017 | The Economist
Sprint To Find Zika Vaccine Could Hinge On Summer Outbreaks
23 Feb 2017 | Kaiser Health News
To Test Zika Vaccines, Scientists Need A New Outbreak
23 Feb 2017 | NPR
Officials confirm 5 more cases of Zika-related birth defects in US
17 Feb 2017 | CIDRAP



Information Portals

WHO: Zika Virus and complications
WHO: Zika: mapping the emerging evidence
Brazilian Ministry of Health's epidemiology portal
Please see our collaborative website on Zika Virus for more information.



Updates and guidelines
The Ministry of Health of the Kingdom of Saudi Arabia has confirmed 7 new cases of MERS-CoV between 17-23 February 2017. For daily reports, please visit the MOH website, here. Ebola and other haemorrhagic fevers

Flu and respiratory infections

Updates and guidelines
New measures to protect against Avian Flu
24 Feb 2017 | DEFRA, APHA, FSA & PHE
Seasonal flu vaccine uptake in GP patients: 1 September 2016 to 31 January 2017
23 Feb 2017 | PHE
FluWatch report:  February 5, 2017 to February 11, 2017 (week 6)
17 Feb 2017 | PHAC

News and Media
H7N9 surge in China prompts high-level call for market closures
23 Feb 2017 | CIDRAP
Four countries report H5N1 as H5N8 detections continue
22 Feb 2017 | CIDRAP
Bird flu strain hitting China may be getting more dangerous
21 Feb 2017 | New Scientist
H7N9 analyses hint at genetic mutations, drug resistance
20 Feb 2017 | CIDRAP
Vietnam reports H5N6 and H5N1 outbreaks as Europe battles more H5N8
20 Feb 2017 | CIDRAP


Other topics in infectious diseases

News and Media
Brazil's yellow fever outbreak shows signs of slowing but tops 1,200 cases
17 Feb 2017 | PAHO
Bill Gates 'hopeful' for global pandemic response plan
17 Feb 2017 | BBC


Global research platforms receive €30M to combat Zika

Oxford --21 October 2016, ISARIC members are part of two successful bids to the European Union’s Horizon 2020 Research and Innovation Programme that will set up multinational and multi-disciplinary research consortia to combat Zika virus (ZIKV) infection and build pandemic ... Read more

ISARIC Statement - EDCTP Collaborations

The recently launched EDCTP call Research and Clinical Management of Patients with PRD epidemics in sub-Saharan Africa encourages applicants to work with national, regional, and international initiatives such as ISARIC and PREPARE Europe. Successful applications will have gone through a ... Read more

Chair's Message

New Chair Peter Horby's first message as ISARIC Chair

Dear Colleagues, I am delighted to be the new Chair of ISARIC and “thank-you” to the many members who have sent messages of support and encouragement. I would like to start my tenure by expressing gratitude on behalf of ISARIC ... Read more

CCP UK Activation Week

All related documents are avaliable online

Calling all participating UK sites - all documents related to the CCP UK Activation Week are made avaliable online for download. Recognising the value of maintaining a sleeping study such as the CCP in a state of readiness and to ... Read more

Peter Horby elected new ISARIC chair

As you know, the term of ISARIC Chair Professor Abdullah Brooks ended in March of this year, and so a nominations process was launched to seek his successor. Professor Brooks was eligible for a second term, but decided not to ... Read more

ISARIC Chair Elections 2016 - Call for Nominations

Deadline 13 May 2016

ISARIC is arranging for Chair Elections in 2016, and we are now calling for nominations among our membership. If you want to nominate yourself or someone else, please read this letter from the Nominations Committee and apply by 13 May ... Read more

Updated CRFs for Zika now available

Download v5.3 @

Updated ISARIC/PREPARE Case Report Forms for Zika Virus (version 5.3) are now available. Updates include changes to ensure that no data field is left blank and implementation of recommendations from colleagues. Read more

Not Parachuting, Building Partnerships since 2011

Response to NEJM Perspective 9 March 2016

In response to David L. Heymann, Joanne Liu, and Louis Lillywhite’s Perspective Partnerships, Not Parachutists, for Zika Research, published in the New England Journal of Medicine on 9 March 2016, we would like to inform the outbreak research and public ... Read more

SPRINT-SARI patient recruitment has commenced

The SPRINT-SARI study has commenced recruitment at multiple sites in Europe and North America. This is an important step forward in achieving preparedness to conduct observational studies of Severe Acute Respiratory Illness during future pandemics or regional epidemics. Read more

ISARIC on the open sharing of data

Oxford, 11/02/16 -- ISARIC is encouraging all members to share research data within the ISARIC research community and with external collaborators working in severe emerging infections. ISARIC would like to emphasise the importance of sharing data with national and international ... Read more

EVAg: Standard for molecular detection of Zika available

A quantified freeze-dried genomic standard for molecular detection of Zika virus by molecular methods will be made available via the EVAg website in early February. It is made of an inactivated culture supernatant of strain H/PF/2013 (full sequence of the ... Read more

New Zika Infection website available

The aim of this website is to provide a platform for sharing and developing research priorities, protocols, data capture systems alongside the latest epidemiological and clinical management information about Zika infection. The website came about through a collaboration between a ... Read more